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2003 2
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2007 3
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2010 5
2011 6
2012 2
2013 3
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2016 3
2017 1
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60 results

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Page 1
Genome-wide analyses of early-onset acute myocardial infarction identify 29 novel loci by whole genome sequencing.
Jeon Y, Jeon S, Choi WH, An K, Choi H, Kim BC, Kim W, Lee SY, Bae JW, Hwang JY, Kang MG, Kim Y, Kang Y, Kim YJ, Kim BC, Bhak J, Shin ES. Jeon Y, et al. Among authors: kim bc. Hum Genet. 2023 Feb;142(2):231-243. doi: 10.1007/s00439-022-02495-0. Epub 2022 Nov 6. Hum Genet. 2023. PMID: 36336746
The association between early-onset AMI and rs9357455, which is located upstream of PHACTR1 and regulates inflammation in AMI, was found. Moreover, we identified a lipid metabolism related genetic risk locus, rs5072, in the APOA1-AS gene. This study provides new evidence s …
The association between early-onset AMI and rs9357455, which is located upstream of PHACTR1 and regulates inflammation in AMI, was fo …
A nuclear factor kappa B-derived inhibitor tripeptide inhibits UVB-induced photoaging process.
Oh JE, Kim MS, Jeon WK, Seo YK, Kim BC, Hahn JH, Park CS. Oh JE, et al. Among authors: kim bc. J Dermatol Sci. 2014 Dec;76(3):196-205. doi: 10.1016/j.jdermsci.2014.10.002. Epub 2014 Oct 14. J Dermatol Sci. 2014. PMID: 25455138
OBJECTIVE: In this study, the effects of a NF-kappaB-derived inhibitor tripeptide on the UVB-induced photoaging and inflammation were investigated in vitro and in vivo. METHODS: A NF-kappaB-derived inhibitor tripeptide (NF-kappaB-DVH) was synthesized based on the sequence …
OBJECTIVE: In this study, the effects of a NF-kappaB-derived inhibitor tripeptide on the UVB-induced photoaging and inflammation were …
Heme oxygenase-1/carbon monoxide axis suppresses transforming growth factor-β1-induced growth inhibition by increasing ERK1/2-mediated phosphorylation of Smad3 at Thr-179 in human hepatocellular carcinoma cell lines.
Park SJ, Lee SK, Lim CR, Park HW, Liu F, Kim SJ, Kim BC. Park SJ, et al. Among authors: kim bc. Biochem Biophys Res Commun. 2018 Apr 6;498(3):609-615. doi: 10.1016/j.bbrc.2018.03.030. Epub 2018 Mar 8. Biochem Biophys Res Commun. 2018. PMID: 29524413
Moreover, TGF-beta1-induced cell cycle arrest and up-regulation of cyclin-dependent kinase inhibitors in HCC cell lines were significantly attenuated by overexpression of HO-1 or treatment with tricarbonyldichlororuthenium(II) dimer ([Ru(CO)(3)Cl(2)](2), sugg …
Moreover, TGF-beta1-induced cell cycle arrest and up-regulation of cyclin-dependent kinase inhibitors in HCC cell lines were signific …
Identification and validation of six acute myocardial infarction-associated variants, including a novel prognostic marker for cardiac mortality.
Jeon Y, Jeon S, An K, Kim YJ, Kim BC, Ryu H, Choi WH, Choi H, Kim W, Lee SY, Bae JW, Hwang JY, Kang MG, An S, Kim Y, Kang Y, Kim BC, Bhak J, Shin ES. Jeon Y, et al. Among authors: kim bc. Front Cardiovasc Med. 2023 Jul 3;10:1226971. doi: 10.3389/fcvm.2023.1226971. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37465449 Free PMC article.
Celastrol induces expression of heme oxygenase-1 through ROS/Nrf2/ARE signaling in the HaCaT cells.
Seo WY, Goh AR, Ju SM, Song HY, Kwon DJ, Jun JG, Kim BC, Choi SY, Park J. Seo WY, et al. Among authors: kim bc. Biochem Biophys Res Commun. 2011 Apr 15;407(3):535-40. doi: 10.1016/j.bbrc.2011.03.053. Epub 2011 Mar 23. Biochem Biophys Res Commun. 2011. PMID: 21414301
We previously demonstrated that celastrol, a quinone methide triterpenoid derived from the medicinal plant Tripterygium wilfordii, exerts its anti-inflammatory activity through up-regulation of heme oxygenase-1 (HO-1) expression in the keratinocytes. In this study, …
We previously demonstrated that celastrol, a quinone methide triterpenoid derived from the medicinal plant Tripterygium wilfordii, exerts it …
Geldanamycin inhibits TGF-beta signaling through induction of Hsp70.
Yun CH, Yoon SY, Nguyen TT, Cho HY, Kim TH, Kim ST, Kim BC, Hong YS, Kim SJ, Lee HJ. Yun CH, et al. Among authors: kim bc. Arch Biochem Biophys. 2010 Mar 1;495(1):8-13. doi: 10.1016/j.abb.2009.12.003. Epub 2009 Dec 6. Arch Biochem Biophys. 2010. PMID: 19995547
In this study, we investigated the mechanism of inhibition of TGF-beta signaling by the Hsp90 inhibitor geldanamycin (GA). Treatment with GA suppressed TGF-beta signaling, as evidenced by inhibition of TGF-beta-induced phosphorylation and transcriptional acti …
In this study, we investigated the mechanism of inhibition of TGF-beta signaling by the Hsp90 inhibitor geldanamycin (GA). Treatment …
Itch E3 ubiquitin ligase positively regulates TGF-beta signaling to EMT via Smad7 ubiquitination.
Park SH, Jung EH, Kim GY, Kim BC, Lim JH, Woo CH. Park SH, et al. Among authors: kim bc. Mol Cells. 2015 Jan 31;38(1):20-5. doi: 10.14348/molcells.2015.2120. Epub 2014 Dec 16. Mol Cells. 2015. PMID: 25518932 Free PMC article.
Although non-Smad signaling pathways are being increasingly reported to play many roles in TGF-beta-mediated biological processes, Smads, especially receptor-regulated Smads (R-Smads), still play a central mediatory role in TGF-beta signaling for epithelial-mesenchy …
Although non-Smad signaling pathways are being increasingly reported to play many roles in TGF-beta-mediated biological processes, Sm …
Genipin up-regulates heme oxygenase-1 via PI3-kinase-JNK1/2-Nrf2 signaling pathway to enhance the anti-inflammatory capacity in RAW264.7 macrophages.
Jeon WK, Hong HY, Kim BC. Jeon WK, et al. Among authors: kim bc. Arch Biochem Biophys. 2011 Aug 15;512(2):119-25. doi: 10.1016/j.abb.2011.05.016. Epub 2011 May 30. Arch Biochem Biophys. 2011. PMID: 21658364
This study aimed to elucidate the anti-inflammatory mechanism of genipin, focusing particularly on the role of heme oxygenase-1 (HO-1), a potent anti-inflammatory enzyme. In RAW264.7 cells, genipin increased HO-1 expression and its enzyme activity via …
This study aimed to elucidate the anti-inflammatory mechanism of genipin, focusing particularly on the role of heme oxygenase-1 (HO- …
Endoscopic Characteristics of Rugal Hyperplasia and Related Acid Condition in Helicobacter pylori-Infected Stomach.
Kim BC, Song MA, Kwon SH. Kim BC, et al. Clin Endosc. 2021 Jan;54(1):73-84. doi: 10.5946/ce.2020.020. Epub 2020 Dec 15. Clin Endosc. 2021. PMID: 33317224 Free PMC article.
BACKGROUND/AIMS: Rugal hyperplastic gastritis (RHG) is associated with Lauren's diffuse-type gastric cancer (GC) and the accompanying active inflammation is linked to gastric hypoacidity. We tried to establish the steps for identifying high-risk GC patients. ...
BACKGROUND/AIMS: Rugal hyperplastic gastritis (RHG) is associated with Lauren's diffuse-type gastric cancer (GC) and the accompanying active …
Smad7 sensitizes A549 lung cancer cells to cisplatin-induced apoptosis through heme oxygenase-1 inhibition.
Jeon WK, Hong HY, Seo WC, Lim KH, Lee HY, Kim WJ, Song SY, Kim BC. Jeon WK, et al. Among authors: kim bc. Biochem Biophys Res Commun. 2012 Apr 6;420(2):288-92. doi: 10.1016/j.bbrc.2012.02.151. Epub 2012 Mar 6. Biochem Biophys Res Commun. 2012. PMID: 22421218
In the present study, we have demonstrated a proapoptotic function of Smad7 as a negative regulator of survival protein heme oxygenase-1 (HO-1). The HO-1 protein level was elevated in cisplatin-resistant A549 human lung cancer cells and blockade of …
In the present study, we have demonstrated a proapoptotic function of Smad7 as a negative regulator of survival protein heme oxygenase-1 ( …
60 results